OXFORD, Miss. — Amari Davis scored 23 points, Kobe Brown added 15 and Missouri beat Mississippi 78-53.
Missouri won just its fourth game in 19 meetings with Ole Miss since the Tigers joined the Southeastern Conference in the 2012-13 season.
Missouri led by double figures the entire second half.
Ole Miss pulled within 57-47 after a 9-0 run, but the Tigers answered by scoring the next 15 points -- with six points from Brown -- for a 25-point lead with three minutes left.
Javon Pickett and Ronnie DeGray III each had 11 points for Missouri.
Daeshun Ruffin scored 12 points for Mississippi.
